Andrew C Lake Selected Research

Neoplasms (Cancer)

1/2023	SRF617 Is a Potent Inhibitor of CD39 with Immunomodulatory and Antitumor Properties.
1/2023	CD73 Inhibits cGAS-STING and Cooperates with CD39 to Promote Pancreatic Cancer.
1/2020	The Fully human anti-CD47 antibody SRF231 exerts dual-mechanism antitumor activity via engagement of the activating receptor CD32a.
3/2004	The growth arrest-specific gene CCN5 is deficient in human leiomyomas and inhibits the proliferation and motility of cultured human uterine smooth muscle cells.

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Andrew C Lake Research Topics

Disease

4	Neoplasms (Cancer) 01/2023 - 03/2004
1	Neoplasm Metastasis (Metastasis) 01/2023
1	Ischemia 12/2006
1	Leiomyoma (Uterine Fibroids) 03/2004
1	Carcinogenesis 03/2004
1	Vascular Diseases (Vascular Disease) 11/2003
1	Wilms Tumor (Wilm's Tumor) 01/2003

Drug/Important Bio-Agent (IBA)

2	Adenosine Triphosphate (ATP)IBA 01/2023 - 01/2023
2	Adenosine (Adenocard)FDA LinkGeneric 01/2023 - 01/2023
2	Proteins (Proteins, Gene)FDA Link 01/2020 - 03/2004
2	Heparin (Liquaemin)FDA LinkGeneric 12/2006 - 03/2004
1	quemliclustatIBA 01/2023
1	Gemcitabine FDA Link 01/2023
1	Adenosine Triphosphatases (ATPase)IBA 01/2023
1	CytokinesIBA 01/2020
1	Chemotactic FactorsIBA 01/2020
1	Chemokine CCL3IBA 01/2020
1	fucoidanIBA 12/2006
1	Polysaccharides (Glycans)IBA 12/2006
1	Messenger RNA (mRNA)IBA 03/2004
1	Connective Tissue Growth FactorIBA 01/2003
1	Cysteine (L-Cysteine)FDA Link 01/2003

Therapy/Procedure

1	Therapeutics 11/2003